Custom Synthesis is our passion

Custom synthesis has always been a significant part of VXCHEM’s production. In the field of custom synthesis, VXCHEM has its own professional R&D team who dedicated to effective realization of multi-step synthesis in laboratory, pilot and production scale. Thanks to the efficiency of our R&D team and the unreserved support from our business partners, we are proud of our ability to give quick response and solution to customer’s questions. We are dealing with custom synthesis, compound libraries, intermediates and building blocks for research and development.

The preparation of chemicals is always performed with utmost care under the guidelines of our quality control. The products are controlled by analytical methods like HPLC, TLC and NMR as well as by chemical analytical methods. This enables us to ensure the highest purity of the products and to fulfill the specifications of our customers.

The attached list of chemical processes will show you the wide range of reactions that we are able to apply to the synthesis of our products.

Please do not hesitate to contact us for quotations on our products. Enquiries will always be treated confidentially.In fact, if a compound that we can’t synthesize, there will not be in the whole of China.

Summary of the most important procedures that we can carry out in our laboratories:

Acetylations by acetyl chloride and acetic acid anhydride
Alkylations by alkyl halides and alkyl sulfates
Carboxylic ester condensation
Catalytic hydrogenations up to 3 bar (1 L Autoclave)
Catalytic reductions by hydrogen
Chlorinations by thionyl chloride
Cleavage of ethers by BBr3
Diazotizations and Sandmeyer reactions
Eschweiler-Clarke methylations
Esterifications and saponifications
Fluorinations by different fluorinating reagents except elementary fluorine
Formations of ethers by different methods (Williamson, Mitsunobu)
Friedel-Crafts alkylations and acylations
Gabriel synthesis
Haloform reactions
Halogenations and halogen exchange reactions
Hydroborations by 9-BBN, borane-THF and borane-amine complexes
Hydroxymethylations by formaldehyde
Isolations of natural stuffs
Ketone and aldehyde condensation reactions
Knoevenagel condensations
Michael reactions
Nitrations of aromatic rings by nitrating acid mixtures or nitric acid
Nucleophilic substitution reactions
Oxidations by peracids, H2O2, nitric acid and others
Perkin reaction
Purifications of chemicals for special applications
Reactions at low temperatures (up to –78°C)
Reactions using hydrogen chloride
Reactions in an inert gas atmosphere
Reductions by metal hydrides
Reductions by sodium metal
Reductive aminations
Seperation of enantiomers
Silylations
Sulfonations and chlorosulfonations
Synthesis of deuterated compounds
Synthesis of carboxylic acid chlorides by PCl5, PCl3 or SOCl2
Synthesis elaboration for new compounds and known compounds
Synthesis of heterocyclic compounds by various methods
Synthesis of indole derivatives
Synthesis of protected and unnatural amino acids
Synthesis of metal salts of inorganic or organic acids
Synthesis using organometallic compounds (Grignard- and organolithium compounds)
Tailor made solutions and mixtures
Vilsmeier reactions
Wittig- and Wittig-Horner reactions
Wolff-Kishner reductions
and many many more ……

Our starting chemicals, key intermediates and active ingredients are from
Chinese sources. This full integration benefits customer because it saves
customer’s time and cost. We will be pleased to provide this service to all
of our customers in term of confidentiality, quality, time and economy.

WHAT TO EXPECT FROM VXCHEM’S SERVICE

SPECIAL ATTENTION FAST RESPONSE TIMELY DELIVERY COST EFFECTIVENESS COMPETITIVE PRICING

PRODUCTS CAN BE OFFERED FROM VXCHEM